In addition, there is no report in the comparison of chemical profiles in different parts of GL (i.e., fruiting body and spore). Large variations in the chemical components were reported in previous studies and there is no comprehensive study of the content of multiple major triterpenoids in the GL product. More than 400 compounds have been identified in GL with the triterpenoids considered to be the major active components. The extracts made from the fruiting body and spore of naturally grown GL are the most frequently used in commercial products. Ganoderma lucidum (GL), also known as Reishi or Lingzhi, is a medicinal mushroom widely used in traditional and folk medicines.